Sébastien Page, iDownloadBlog:

Whether you want to show off your beautiful wallpaper, or simply want your set up to look different from the millions of other iPhones out there, one of the best way to do that is to add blank icons to your Home screen.

These invisible icons will allow you to create empty spaces on your Home screen to either let the wallpaper shine, or to arrange your app icons in a very specific way.

This tutorial will show you how to create create blank iPhone icons, no jailbreak or hack required.

This is my new favorite way to add blank icons to customize your home screen. Note that you have to re-jump through the hoops if you want to change the blank icons.

In a nutshell, you use iPhone Safari to browse to iempty.tooliphone.net. That site lets you customize your page, as you like.